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Samples of standard solutions of the medicinal substances were prepared using protocols described in the Section The peak purity test sample preparation

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It is not rare to note in affected individuals an association between vitiligo and other autoimmune and autoinflammatory conditions such as alopecia, asthma, Hashimotos thyroiditis, Graves disease, and type 1 insulin-dependent diabetes mellitus indicating the presence of multiple comorbidities (Dahir and Thomsen 2018)

Far from being a single procedural step, a FIH trial is built on a broad body of scientific, regulatory and operational work designed to ensure that the transition from preclinical research to human investigation takes place within a rigorous framework focused on safety, quality and evidence generation