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For the past year and a half, Tandra Cooper Harris and her husband, Marcus, who both have diabetes, have struggled to fill their prescriptions for the medications they need to control their blood sugar

The foundational and mechanistic evidence originates largely from one research group, independent corroboration is limited, and there is no robust placebo-controlled human trial measuring telomere length before and after administration

The comparator groups differed among studies, with some employing placebo controls (e.g., PIONEER-6, Gerstein 2019), others using active comparators such as sitagliptin, glimepiride, DPP-4 inhibitors, or SGLT2 inhibitors, and some utilizing standard care or intensive lifestyle interventions as the control

The most important "diet" on GLP-1 is not a named plan but rather the protein-first, whole-foods approach that consistently delivers results