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For hair, PDRN is most useful in patients whose hair loss has an inflammatory or post-inflammatory component: telogen effluvium after stress, hair loss following autoimmune flares, recovery after hair transplant procedures, or scalp inflammation accompanying conditions like seborrheic dermatitis

And while you can count your morning OJ as a good defense for your bod, the best way to achieve vitamin Cs protection and benefits for skin is to apply it topically

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Fasano A, Not T, Wang W et al (2000) Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease