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Perioperative implications were evaluated with emphasis on orthopaedic surgical risk domains relevant to total joint arthroplasty (TJA), including wound complications, hematoma formation, immune modulation, infection susceptibility, heterotopic ossification, and implant fixation considerations

While non-activated microglia preferentially use oxidative phosphorylation, activated microglia undergo a metabolic reprogramming, with increased glucose uptake and strengthening of anaerobic glycolysis, to increase ATP production [65]

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The compound dosing chart for tirzepatide provides detailed unit counts across all vial sizes and concentrations