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376 TRIM24 Tripartite motif 24 protein (TRIM24) also known as transcriptional intermediary factor 1 (TIF1) is a transcriptional co-activator that has a N-terminal TRIM domain with three zinc-binding domains a RING, a B-box type 1 and a B-box type 2 and also a coiled region with potential self-assembly properties, 377 a C-terminal region containing a PHD finger, a bromodomain, and a nuclear receptor interaction box