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In animal studies, Dihexa was found to be approximately 1,000 times more potent than BDNF (brain-derived neurotrophic factor) at promoting synapse formation

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Multicenter phase I trial of a DNA vaccine encoding the androgen receptor ligand-binding domain (pTVG-AR, MVI-118) in patients with metastatic prostate cancer

however, this analysis was conducted in general obesity and diabetes populations, not IBD-specific cohorts, and its findings may not directly translate to patients with underlying intestinal inflammation (97)