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For example, decreased phosphorylation of H3S10 in diabetes may lead to overexpression of pro-inflammatory genes, exacerbating diabetic complications [191]

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La evidencia reciente ha demostrado beneficios teraputicos en: eventos cardiovasculares mayores, insuficiencia cardaca con fraccin de eyeccin preservada, prevencin de diabetes, apnea obstructiva del sueo, enfermedad arterial perifrica, enfermedad renal crnica y esteatohepatitis asociada a disfuncin metablica (MASH)