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To obtain the specific labeling patterns, intracellular metabolites were extracted and analyzed using GC/MS to determine multiple ion detections (MIDs) (corrected for natural isotope abundance), which reflect relative metabolic fluxes 28
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This study has some limitations including that the number of individuals for whom cardiometabolic measures were available in the AEMR and LAAD databases was quite low, with the exception of BP, which prevented us from evaluating the other cardiometabolic outcomes for the BMI and HbA1c subgroups
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