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Part of the challenge is that the cost of the prescriptions, which is often not covered by insurance, pushes people to seek less expensive alternatives

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The complications of Melanotic Macules may include the following: The longstanding skin patches can cause emotional stress and cosmetic concerns in some individuals The appearance of the pigmented macules may induce a fear of melanoma (which is a type of skin cancer) Complications that arise from an underlying genetic condition/syndrome Treatment complications and medication side effects How is Melanotic Macules Treated

What they did: They produced gastric ulcers in rats using common anti-inflammatory drugs, diclofenac, ibuprofen, indomethacin and aspirin