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[6] In rat wound models, it produced concentration-dependent increases in connective tissue accumulation with collagen synthesis twice that of non-collagen proteins

The concept was first established by Tan et al

The discovery has revealed that natural plant polysaccharides possess the ability to exert antidepressant effects through the regulation of neurotransmitters and their receptors, modulation of the HPA axis, control of inflammatory responses, management of oxidative stress, modulation of neurotrophic factors, regulation of gut microbiota and tryptophan metabolism, as well as other pathways

Chollangi S, Wang J, Martin A, Quinn J, Ash JD