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GnRH analogs are often prescribed when oral contraceptives and/or progestin analogues fail to produce successful outcomes

Falta de respuesta adecuada : Si despus de 3-6 meses de tratamiento a la dosis teraputica completa no se observan mejoras significativas en el control glucmico (reduccin de HbA1c de al menos 0.5-1%) o en el peso corporal (prdida de al menos 5% del peso inicial cuando se prescribe para manejo de peso), debe consultar con su mdico

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Studies have shown that alpha diversity of gut microbiota was significantly decreased in PCOS patients (48, 49)