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Graphical abstract Similar content being viewed by others Introduction The word fatigue originates from the Latin verb fatigare which means to tire and which can be defined as an extreme tiredness due to physical or mental exertion or illness (Phillips 2015

In addition, men without full cystic fibrosis but who harbor mutations in the related gene (known as CFTR) are prone to low sperm counts and obstruction of the epididymis and ejaculatory duct

After the operation, the skin was sutured layer by layer and disinfected

However, some users also report mild fatigue, mood swings, and sleep disruptions, even though these are less common than gastrointestinal side effects