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GLP-1 medications are prescription drugs that help control appetite and blood sugar levels

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GLP-1 receptor agonists are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

Best For Patients who want maximum efficacy with an FDA-approved medication Patients who have plateaued on semaglutide and need a stronger option Patients with significant weight to lose (50+ pounds) Patients with insulin resistance, metabolic syndrome, or type 2 diabetes Patients who have the budget for the more expensive option See our full tirzepatide service page and our deep comparison of the difference between tirzepatide and semaglutide