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The relationship between the gut microbiota and thyroid disorders

Notably, it can increase Treg cells and decrease the differentiation of Th17 cells in lupus-prone mice, which contribute to suppresses the development of glomerulonephritis and skin diseases (180, 181)

Additionally, genes responsible for oxidative protein folding and glycoprotein processing (Pdia4, Pdia6, Ero1l, Uggt1, Ostc, Stt3a, Ganab, Rpn1, Lman1, Tmem258, Ggt6, Wfs1) were consistently downregulated

These hormonal alterations, which could be linked to menstrual cycles, pregnancy, or even certain medications like birth control pills, have the potential to disrupt the delicate balance of microorganisms in the vaginal environment