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Although TAGs do not function as signaling molecules per se, the lipid intermediates generated during lipogenesis and lipolysis influence intracellular insulin signaling and participate in progression of IR

However, patients in high-risk groups (over 60, concurrent metformin use, vegan diet, post-bariatric surgery) may benefit from additional supplementation

Biosci Biotechnol Biochem 72(4):959967 Azzini E, Ruggeri S, Polito A (2020) Homocysteine: its possible emerging role in at-risk population groups

When taking into account recurrent episodes and seasonal variation, NTHi accounts for approximately 60% of cases (Haggard, 2008