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But until now, there hasnt been any data from large epidemiologic studies. Results showed use of GLP-1 agonists compared with bupropion-naltrexone correlated with a 9.09 (95% CI, 1.25-66), 4.22 (95% CI, 1.02-17.4) and 3.67 (95% CI, 1.15-11.9) times higher risk for pancreatitis, bowel obstruction and gastroparesis, respectively

Yang Y, Liu T, Hu C, Xia H, Liu W, Chen J, et al

Symptoms, which typically emerge before six months of age, include failure to thrive, decreased appetite, lethargy, anemia, and GI issues like diarrhea

discuss any visual changes with your clinical team [16] [17] Thyroid considerations: Animal studies with GLP-1 receptor agonists have shown an increased incidence of thyroid C-cell tumours in rodents