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The time of day is less important than consistency

These often affect the gastrointestinal tract, for example nausea, diarrhoea, constipation, vomiting or abdominal discomfort

Early use of n-acetylcysteine with nitrate therapy in patients undergoing primary percutaneous coronary intervention for ST-segment-elevation myocardial infarction reduces myocardial infarct size (the NACIAM Trial [N-acetylcysteine in Acute Myocardial Infarction])

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