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Engineered probiotics have also shown advantages in inflammatory models involving nanoplastics, including modulation of the microbiome, suppression of inflammation, and prevention of bacterial colonization [158, 159]

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PMID: 42260976 Nat Commun 2019 Jun 20;10(1):2701

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Another clinical trial utilized NR to help ameliorate heart failure (HF), which is also characterized by a decline in NAD + levels in whole blood 317,318

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