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Monitoring the quantity and functional changes of these specific immune cell subsets could provide a more precise assessment of immune status than NLR, thereby more accurately predicting the risk of infectious complications

However, there are IGF-I receptors on the nonparenchymal cells[89, 90] and it has been reported that IGF-I stimulates both DNA synthesis[91, 92] and the production of hepatocyte growth factor (HGF) in hepatic stellate cells in vitro [87]

It was originally developed to help reduce bleeding by preventing blood clots from breaking down