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Independent Data Safety Monitoring Board (DSMB) To compare the safety of SAMe versus placebo, interim safety analyses will be performed following the collection of the final visit data in the first 20 participants, and after 40 participants

Subsequently, CON rose significantly to a second peak at 9 h pi and returned to baseline values, whereas CAR remained unchanged until the end of the study

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The Gut Repair Stack Clinical Goal: To heal intestinal hyperpermeability ("leaky gut"), reduce gut-derived inflammation, and restore the integrity of the mucosal lining