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GH Secretagogue Comparison Compound Class Receptor FDA Status Ipamorelin GHRP (ghrelin mimetic) GHS-R1a Not approved CJC-1295 GHRH analog GHRH-R Not approved Sermorelin GHRH analog GHRH-R Previously approved (Geref, discontinued) Tesamorelin GHRH analog GHRH-R FDA approved (Egrifta) GHRP-2 GHRP (ghrelin mimetic) GHS-R1a Not approved GHRP-6 GHRP (ghrelin mimetic) GHS-R1a Not approved Selectivity Profile: The Key Research Differentiator What makes Ipamorelin stand out among GHRPs is its endocrine selectivity

10.1016/j.freeradbiomed.2010.08.010 109 SahayA.ScobieK

cuspidatum, has been shown to mitigate inflammation and OS in rats with AKI models

NRF2 is then able to translocate into the nucleus and activate the expression of genes critical for protecting the cell