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Given that Im a research hound, I looked into the origins of this ancient vegetable and found that it was first cultivated about 2,500 years ago in Greece

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502 In mice with type 2 diabetes, sulforaphane inhibits ferroptosis by inducing Nrf2-mediated metallothionein expression, thereby preventing diabetes-related cardiac inflammation, oxidative damage, and hypertrophy

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References View all references + Sikiri, P., et al

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Thus these changes must come from some other effect of chromosome 21 trisomy

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