semaglutide gray Crystal structure of the peptide backbone (gray) in Semaglutide Peptide - GLP1 receptor

Clinical trials have shown that semaglutide and liraglutide are generally well tolerated, with gastrointestinal disorders being the most commonly reported AEs, including nausea, diarrhea, vomiting, and constipation, leading to dose reduction or temporary treatment interruption in 12.5% of study participants [40,41,42]

Certain natural plant compounds have been shown to support GLP-1 production in lab and animal studies: Flavonoids like (-)-epicatechin (found in dark chocolate) and anthocyanins (from berries and purple veggies) have been shown to increase GLP-1 and improve metabolism via the PKA signaling pathway (Cremonini et al., 2021)

Of course, always discuss everything with your doctor

Endocrinology 139 , 26052614 (1998)