chapter 77, 8th edn
The most common side effects are gastrointestinal nausea, vomiting, diarrhea, and constipation and they are tightly linked to slowed gastric emptying and to dose escalation
First, Sensing and Destruction: COFs, equipped with precisely integrated sensitizing units, efficiently respond to external stimuli (e.g., light, ultrasound, radiation) or endogenous triggers (e.g., H 2 O 2 ), generating intense local biochemical effects such as bursts of ROS, hyperthermia, or DNA damage ( Figure 2 ) (155, 156, 166)
This study administered a culture of 13 common fecal bacteria via colon infusion, resulting in 70% of patients responding positively after four weeks