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Because glutamate is the major excitatory transmitter in the human brain, derangements in glutamate metabolism or receptor activation have been implicated in a wide variety of pathologic conditions

If initial daily administration has been maintained for more than 2 weeks, extending this washout to 57 days allows fuller recovery from any receptor downregulation that may have occurred

2.12 Morphological and histological study Mouse dorsal skin tissues were fixed in 4% (v/v) formaldehyde, embedded in paraffin, sliced into 5-m sections (HistoCoreBIOCUT

Improved glucose tolerance in Zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide