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Folic acid supplementation can alleviate the symptoms of anemia in patients with dihydrofolate reductase deficiency, but this does not correct the deficiency of tetrahydrofolate in the brain, often leaving neurological sequelae

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Key effects associated with TB-500: Soft tissue repair support Cell migration Angiogenesis Reduced inflammatory signaling Improved tissue remodeling Possible cardiac and neurologic repair effects in preclinical models Like BPC-157, most TB-500 data remains preclinical

The story began in the 1990s in Zagreb