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Neurotrophic factors (NGF, BDNF, NT-3) are essential for nerve survival, maintenance, and regeneration
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Mechanism of action in the mouth (oral cavity) Wound healing: Stimulates fibroblast activity, collagen synthesis, and keratinocyte migration, accelerating soft tissue repair (important for periodontal disease, oral ulcers, or mucosal trauma) 2 Anti-inflammatory modulation Reduces neutrophil and macrophage overactivation, limiting collateral damage to gum tissue 3 : Bone and ligament support: Early studies suggest BPC-157 promotes tendon-to-bone healing and osteogenesis, potentially relevant for periodontitis-related bone loss or implant integration
On the whole, animal studies have found BPC-157 to have a favorable safety profile at research amounts, with no significant toxic effects reported in short- to medium-term rodent studies
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