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In addition, combination of ganitumab with metformin is being tested in an ongoing I-SPY2 trial, which aims to identify most effective agents to treat various types of breast cancer and learn about the predictors of treatment response [155]

Wong et al., 2012)

Because T4 is a small, naturally occurring peptide that functions across multiple tissues, it may offer a more practical therapeutic approach compared to complex interventions such as stem cell therapies