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While carbonic anhydrases generally facilitate the interconversion of CO 2 and HCO 3 , CA9 is a membrane-bound isoenzyme traditionally associated with pH homeostasis in tumor niches ( 2 Materials and methods 2.1 Animals Procured from Charles River (Beijing, China), C57BL/6 male mice (1822 g body weight) at 68 weeks of age were utilized for this study

Carotenoids Carotenoids are liposoluble pigments found in plants, algae, and animals, classified into carotenes and xanthophylls, which exhibit diverse structures influencing their biological functions 187

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