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Both are potentially harmful for an endurance athlete who needs to consume 60-90g of carbohydrates per hour during a marathon or Ironman
As clinicians increasingly encounter patients with IBD as well as obesity, diabetes, or metabolic liver disease, there is a clear need to synthesize what is known about safety, metabolic effects, and IBD-specific outcomes to support evidence-informed clinical decision-making, explains senior investigator and study author Jolle St-Pierre, MD, PhD, FRCPC, a clinical assistant professor in the Division of Gastroenterology and Hepatology at the University of Calgary, Canada, in an email to Gastro Today
Individual results may vary depending on factors such as starting weight, dose, adherence, diet and exercise habits and how well the treatment is tolerated
In the Phase 2 trial, retatrutide 12 mg weekly produced mean weight loss of 24.2% at 48 weeks, with the highest-dose group achieving 28.7% at the same timepoint in the TRIUMPH-4 Phase 3 trial
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