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Ethics statement The animal study was approved by this study was approved by the Animal Ethics Committee of Shahid Beheshti University (ethical code: IR.SBU.REC.1402.152)

Mesenteric venous thrombosis, involving blood clot development within the mesenteric veins, constitutes another prominent cause of intestinal ischemia

Indeed, in both studies, the highest frequency of TEAEs was in the normal function groups, possibly owing to the smaller sample sizes in the more severe impairment groups, or alternatively because participants with more serious health concerns, such as those with severe renal or hepatic impairment, may be less likely to notice or report mild or moderate TEAEs, as observed in populations with cancer [21]

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