novo nordisk's semaglutide failed to slow alzheimer's disease progression

novo nordisk's semaglutide failed to slow alzheimer's disease progression A Critical Appraisal of the Evoke and Evoke+ trials for glp1 #drugdevelopment #clinicaldevelopment #alzheimersdisease #alzheimersresearch

Name: novo nordisk's semaglutide failed to slow alzheimer's disease progression A Critical Appraisal of the Evoke and Evoke+ trials for glp1 #drugdevelopment #clinicaldevelopment #alzheimersdisease #alzheimersresearch
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10.1124/jpet.114.220277 J Pharmacol Exp Ther

Inhibition of GLS expression results in reduced immunoglobulin (Ig) G and IgM antibody production, and glutaminase blockade decreased downstream mTOR activation and attenuated IL-10 secretion [121, 141, 142]