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Do not rub the point of insertion, as this can cause bruising

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We summarize mechanistic insights across cellular and molecular domains, critically appraise preclinical and clinical findings, and discuss translational challenges that include bioavailability and brain penetration, study heterogeneity, biomarker guided stratification, and pediatric safety

In addition to physiological changes that occur with aging, and also social risk factors, the elderly population is at a risk for protein malnutrition and vitamin deficiency