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Current evidence suggests that benefitsboth glycemic control and weight reductionare maintained with continued treatment, but discontinuation frequently results in weight regain and worsening of metabolic parameters

A 2016 review by Sikiric and colleagues in Current Neuropharmacology framed BPC-157's effects within a brain-gut axis model, while a 2024 review by Sikiric and colleagues in Pharmaceuticals (Basel) examined the peptide's relationships with multiple neurotransmitter systems

Supplements can support behaviour and performance, but they do not replace the deficit

This may be attributed to the target site being located just upstream of the last five base pairs of the open reading frame at the C-terminal end of exon 14 in the Alb gene (Fig