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But basically zero human data

The identification of a constitutive NADPH-independent cytosolic disulfide reductase system in mammals Based on the well-established requirement for the NADPH-dependent disulfide reductase systems in microbial models, as discussed above, it seemed to be a foregone conclusion that mammalian cells would also require the presence of at least one of the two NADPH-dependent cytosolic disulfide reductases for survival

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The role of the intestinal mycobiota is under investigation, and the importance of the fungal fraction of the gut can be demonstrated in IBD by a CD biomarker ASCA antibody (anti- Saccharomyces cerevisiae )