candidates for glp-1 Receptor Agonists: Who Are the Best Candidates? Who Is a Good Candidate

Symptoms of B12 deficiency may include Megaloblastic anemia (large red blood cells with abnormal nuclei) Fatigue Paleness Heart palpitations Dementia Weight loss Infertility Numbness and tingling in hands and feet Depression, mania, delirium, psychosis Poor pregnancy and breastfeeding outcomes (neural tube defects, developmental delays, failure to thrive, anemia in offspring) Low red and white blood cell counts or platelets Glossitis of the tongue Erectile dysfunction or bowel/urinary incontinence Recommended Daily Intake for B12 Recommended Dietary Allowance (RDA) Daily B12 requirements depend on age, sex, and dietary intake (5) Assessing B12 Status Typically serum B12 levels are used to determine vitamin B12 deficiency (keep in mind normal value ranges may vary slightly depending on the laboratory)

The department expects to make regulatory decisions on more of these submissions in the coming weeks and months

Dev Med Child Neurol 2005

The oligonucleotides were supplied by Metabion GmbH (Planegg/Steinkirchen, Germany), and the PCR kit containing ALLin HiFi DNA Polymerase was purchased from highQu GmbH (Kraichtal, Germany) and used according to the manufacturers instructions