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Beyond physical symptoms, dermatologic injuries can lead to secondary psychological problems such as anxiety, anger, the contagious nature of certain dermatologic diseases poses not only a threat to individual wellbeing but also causes widespread panic and social discrimination, causing great physical and psychological pain to patients (Feldo et al., 2022)

Cellular metabolites were extracted with 250 L of 80% MeOH at 80 C for 15 min

Moreover, a mass spectrometry-based metabolomic analysis was carried out to ascertain whether fructose intake also influences the homeostasis of amino acids, amino acid derivatives and other polar metabolites, particularly the main neurotransmitters, in the frontal cortex