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At the level of thyroid hormone synthesis, TNF- can directly inhibit the activity of thyroid peroxidase (TPO), and IL-1 stimulates iodothyronine 5-deiodine activity in the liver to affect the metabolism of thyroid hormone (Fujii et al., 1989)

American Journal of Epidemiology, 167 (9), 1070

It is produced by the liver which is used by the various parts of the body involving building of tissue, repairing and assistance for certain biochemical synthesis and proteins, and promoting normal functionality of your immune system

While the precise mechanisms may vary from one condition to another, there are common threads in how neurotransmitter imbalances manifest as neurological and psychiatric symptoms