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Specifically, palmitoylation at the Cys130 site (Cys126 in mice), which is catalyzed by PATs such as DHHC1/5/7, is required for the targeting of NLRP3 to the Golgi apparatus and its response to activation signals [103,104,105]

Peer review Peer review information Nature Communications thanks Lin Yuan and the other anonymous reviewers for their contribution to the peer review of this work

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