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Notably, the azo-containing chemotherapeutic drug procarbazine for the treatment of Hodgkins lymphoma and brain cancers was found to interact through a similar mechanism of action involving the transformation of GSH to GSSG and regeneration of the catalyst through a reaction with O 2 38,39 , providing feasibility of the proposed catalysis

Experimental animals were housed individually and had free access to drinking water

The limitations are serious

In the review, we highlight recent advancements in our understanding of how UA exerts neuroprotective effects on neurodegenerative diseases and emphasize the dual roles of UA in managing oxidative stress and neuroinflammation