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Summary of Reported Deaths According to data published by the UKs Medicines and Healthcare Products Regulatory Agency (MHRA) and reviewed by medical outlets including The BMJ and The Independent , a total of 82 deaths have been reported in connection with GLP-1RA drugs as of January 31, 20252

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Orlistat, phentermine/topiramate, naltrexone/bupropion, and the incretin-based drugs liraglutide and semaglutide, both GLP-1 receptor agonists (GLP-1RA), and tirzepatide, a biased dual GIP/GLP-1 receptor agonist, are currently both FDA and EMA approved for the management of non-syndromic obesity 10