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This can lead to copper sequestration in misfolded fibrils along with copper deficiency in the mitochondria, causing impaired energy production ( At least one histidine residue is present in the majority of amyloidogenic proteins, and these histidine residues interact with copper in important ways, influencing their conformational shape

doi: 10.1152/ajpcell.00108.2005 176 KongFYoungLChenYRanHMeyersMJosephPet al

The duration of supplementation ranged from three to nine months, with outcomes evaluated at defined intervals of three, six, or nine months

Individuals with digestive conditions such as Crohns disease, celiac disease, or those whove undergone certain procedures affecting the stomach or small intestine may struggle with absorption