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GLP-1 (Glucagon-like Peptide-1) is a naturally occurring hormone that plays a key role in appetite regulation, digestion, and blood sugar control

Agius E, Lacy KE, Vukmanovic-Stejic M, Jagger AL, Papageorgiou AP, Hall S, Reed JR, Curnow SJ, Fuentes-Duculan J, Buckley CD, Salmon M, Taams LS, Krueger J, Greenwood J, Klein N, Rustin MH, Akbar AN

Its unknown whether the same will be seen in humans, but semaglutide is not recommended for anyone with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)

According to FAIR Healths 2025 analysis of more than 51 billion commercial insurance claims, the share of adults prescribed a GLP-1 medication increased from 0.9% in 2019 to 4% in 2024