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While this approach is appropriate for capturing early oxidative and micronutrient-related alterations associated with disease severity, it does not allow evaluation of temporal dynamics, recovery patterns, or causal relationships, which would require longitudinal follow-up

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Additionally, a recent study (198) suggests that R-SH, an OSM, could serve as a biomarker for IBD, proving more sensitive than C-reactive protein (CRP) in detecting moderate endoscopic activity, though less sensitive than fecal calprotectin, with age and albumin levels as potential confounding factors, and indicates that R-SH may improve IBD monitoring

High intestinal isoleucine is a potential risk factor for food allergy by regulating the mTOR/AKT pathway in dendritic cells