Typically, they contain botanical extracts like green tea or green coffee extract, as well as other ingredients like vitamins or amino acids
They are primarily prescribed for the management of type 2 diabetes mellitus (semaglutide [Ozempic], liraglutide [Victoza], dulaglutide [Trulicity], exenatide [Byetta, Bydureon BCise]) and, with separate formulations, for weight management in adults with obesity or overweight with weight-related comorbidities (semaglutide [Wegovy], liraglutide [Saxenda])
GLP-1 comparison guide: Ozempic vs Wegovy vs Mounjaro vs Zepbound Knowing the differences between these medications is important, but can also be confusing
Initial studies in rats caused concerns over GLP-1 RAs causing thyroid cancer, but human studies are less clear on whether it is a concern.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)