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If you notice changes in cycle regularity, they may relate to weight loss itself (a known metabolic effect) rather than the medication

That is exactly how the medical weight loss programme at Nirvana Clinic is run

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Nails should be kept short and local trauma such as nail biting or sucking should be avoided to prevent the Kebner phenomenon.6 Therapeutic options include urea-based creams, clobetasol nail lacquers, calcipotriol, tazarotene, topical corticosteroids or combination therapies, methotrexate, and, in severe cases, biologic drugs.8,31 Intralesional corticosteroids are rarely used in children due to the pain associated with infiltration