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These agents produce a mild sodium channel blockade and are most effective in ischemic or depolarized myocardial tissue, such as in acute myocardial infarction or post-reperfusion states (11)(12)

However, the existing body of research suggests that DSIP could be a promising tool in the treatment of sleep disorders, chronic pain, and neurodegenerative diseases.

Rather than producing a high spike in circulating hormones, this system functions as a gradual and subtle braking mechanism that helps regulate appetite over time

McClure J Diet Suppl 2010)