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SGLT2 inhibitors, DPP-4 inhibitors, thiazolidinediones and a significant number of studies centered around dietary supplements ranging from probiotics to walnuts

268 More advanced imaging of the uterus (saline infusion sonogram or hysteroscopy) and fallopian tubes (hysterosalpingogram or laparoscopy) may be recommended to rule out uterine problems, endometriosis, adhesions, or other blockages, especially in women with normal antral follicle counts and AMH levels

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Amelanotic forms may require use of immunohistochemical identification: S-100 protein, HMB-45, Melan-A expression Diagnosis Biopsy High index of suspicion Differential Diagnosis Mucosal nevus Extrinsic pigmentation Melanoacanthoma Kaposis sarcoma Vascular malformation Amalgam tattoo Mucosal melanotic macule Treatment Surgical excision Marginal parameters related to depth of invasion and presence of lateral growth Wide surgical margins