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Conclusions This study provides mechanistic evidence to demonstrate the anti-inflammatory effects of GLP-1R activation induced by liraglutide in a monoiodoacetate-induced knee OA rat model through the activation of the PKA/CREB pathway

In the brain, GLP-1 is thought to be involved in memory formation as well as in the control of appetite (1,3)

Individuals who already receive GLP-1 medications through their existing Medicare prescription drug coverage or are eligible for separate Medicare GLP-1 coverage, Medicare Part D, are excluded

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