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In addition, reduced MBOAT7 expression in TT carriers led to increased levels of inflammatory cytokines (TNF- and MCP-1) after stimulation with TLR2, TLR4, and TLR9 compared to controls [276]

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When rats were administered bupropion at oral doses of up to 300 mg per kg per day (approximately 7 times the MRHD on a mg per m2 basis) prior to mating and throughout pregnancy and lactation, there were no apparent adverse effects on offspring development

Ces rsultats, non rviss par les pairs, proviennent dune tude nomme SELECT (nouvelle fentre), qui a port sur 17 604 participants qui ont reu des injections de Wegovy ou d'un placbo